Crisper technology can improve lizard tails

An experiment in re-breeding a lizard’s tail has been remarkably successful. Photo: File

California: Lizards specialize in regenerating their organs, especially their tails. However, the tail is not the same as before, it has only one bone and the nerves are missing, but now, with the help of crisper stem cell technology, not only has the lizard been able to form an organ closer to its original tail, but it can be applied to other organs as well.

Scientists at the University of Southern California (USC) have successfully experimented with regenerating the tail, bones and other nerves in lizards through stem cell therapy. It is hoped that sooner or later human beings will benefit in this way.

In the process of saving lives, lizards flutter their tails and disappear. After a few weeks or months, the lizard has a new tail, but it is a replica. It forms a solid tube of crunchy bone, while the original tail emanates from the cerebellum, which contains the bones as well as nerves and veins.

The tail of lizards is formed in the process of ovulation, but its full growth occurs in puberty. Neural stem cells (NCS) play an important role in this. In the same way, the same cells are active in the formation of the second tail. Experts have observed that at birth, a molecular signal emanates from inside the tail and becomes a complete and real tail, while after the tail is broken, signals emanate from the top and sides of the tail.

Experts considered the process in several ways and even stopped the signal but did not make the upper part of the tail. He then made some changes to the embryonic neural stem cell with CRISPR technology. Now when these cells were inserted into the root of the tail of an adult lizard, there was tremendous success, meaning that not only did it grow like a ‘real’ tail, but it also had bones and nerves on its upper part.

While this is good news for lizards, it will also pave the way for regeneration of organs and nerves in humans. According to research expert Thomas Losito, the study could help regenerate organs, but the human case is a bit more complicated. But initially it will only be used to heal wounds.

It should be noted that most of the fistulas and wounds in diabetic patients are very difficult to heal and sooner or later there will be progress in their treatment.

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